The risk of valvular regurgitation in patients with Parkinson's disease treated with dopamine receptor agonists
Identifieur interne : 000117 ( Main/Exploration ); précédent : 000116; suivant : 000118The risk of valvular regurgitation in patients with Parkinson's disease treated with dopamine receptor agonists
Auteurs : Vibeke Guldbrand Rasmussen [Danemark] ; Karen Stergaard [Danemark] ; Erik Dupont [Danemark] ; Steen Hvitfeldt Poulsen [Danemark]Source :
- Movement Disorders [ 0885-3185 ] ; 2011-04.
English descriptors
- KwdEn :
Abstract
Objectives:: Several observational studies suggest an association between treatment with ergoline‐derived dopamine agonists and valvular regurgitation. In this article, we present an overview of the literature and conduct a meta‐analysis. Methods:: Observational studies addressing the frequency of moderate or severe valvular regurgitation among ergoline‐treated patients with Parkinson's disease were considered for a meta‐analysis. Pooled risk estimates and the risk of increased pulmonary artery pressure were calculated. Results:: The pooling of data from well‐designed observational studies documented that both pergolide (RR = 3.05 [1.71–5.44]) and cabergoline (RR = 6.38 [3.17–12.81]) represent a substantially increased risk of developing moderate to severe valvular regurgitation. In addition, pergolide, but not cabergoline, was associated with an increase in pulmonary artery pressure. Conclusions:: The present meta‐analysis confirmed a statistically significant association between pergolide and cabergoline treatment and the risk of moderate to severe valvular regurgitation. An association between bromocriptine and valvular regurgitation cannot be entirely ruled out. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23470
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The risk of valvular regurgitation in patients with Parkinson's disease treated with dopamine receptor agonists</title><author><name sortKey="Rasmussen, Vibeke Guldbrand" sort="Rasmussen, Vibeke Guldbrand" uniqKey="Rasmussen V" first="Vibeke Guldbrand" last="Rasmussen">Vibeke Guldbrand Rasmussen</name></author><author><name sortKey=" Stergaard, Karen" sort=" Stergaard, Karen" uniqKey=" Stergaard K" first="Karen" last=" Stergaard">Karen Stergaard</name></author><author><name sortKey="Dupont, Erik" sort="Dupont, Erik" uniqKey="Dupont E" first="Erik" last="Dupont">Erik Dupont</name></author><author><name sortKey="Poulsen, Steen Hvitfeldt" sort="Poulsen, Steen Hvitfeldt" uniqKey="Poulsen S" first="Steen Hvitfeldt" last="Poulsen">Steen Hvitfeldt Poulsen</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A3521F2ADEA85DDD6FC91814A070765A51D749C2</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/mds.23470</idno><idno type="url">https://api.istex.fr/document/A3521F2ADEA85DDD6FC91814A070765A51D749C2/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001190</idno><idno type="wicri:Area/Main/Curation">000F91</idno><idno type="wicri:Area/Main/Exploration">000117</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The risk of valvular regurgitation in patients with Parkinson's disease treated with dopamine receptor agonists</title><author><name sortKey="Rasmussen, Vibeke Guldbrand" sort="Rasmussen, Vibeke Guldbrand" uniqKey="Rasmussen V" first="Vibeke Guldbrand" last="Rasmussen">Vibeke Guldbrand Rasmussen</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Cardiology, Aarhus University Hospital, Skejby</wicri:regionArea><wicri:noRegion>Skejby</wicri:noRegion></affiliation></author><author><name sortKey=" Stergaard, Karen" sort=" Stergaard, Karen" uniqKey=" Stergaard K" first="Karen" last=" Stergaard">Karen Stergaard</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Aarhus University Hospital</wicri:regionArea><wicri:noRegion>Aarhus University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Dupont, Erik" sort="Dupont, Erik" uniqKey="Dupont E" first="Erik" last="Dupont">Erik Dupont</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Neurology, Aarhus University Hospital</wicri:regionArea><wicri:noRegion>Aarhus University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Poulsen, Steen Hvitfeldt" sort="Poulsen, Steen Hvitfeldt" uniqKey="Poulsen S" first="Steen Hvitfeldt" last="Poulsen">Steen Hvitfeldt Poulsen</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Cardiology, Aarhus University Hospital, Skejby</wicri:regionArea><wicri:noRegion>Skejby</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-04">2011-04</date><biblScope unit="volume">26</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="801">801</biblScope><biblScope unit="page" to="806">806</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">A3521F2ADEA85DDD6FC91814A070765A51D749C2</idno><idno type="DOI">10.1002/mds.23470</idno><idno type="ArticleID">MDS23470</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson</term><term>dopamine agonist</term><term>ergolines</term><term>fibrosis</term><term>heart valve</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives:: Several observational studies suggest an association between treatment with ergoline‐derived dopamine agonists and valvular regurgitation. In this article, we present an overview of the literature and conduct a meta‐analysis. Methods:: Observational studies addressing the frequency of moderate or severe valvular regurgitation among ergoline‐treated patients with Parkinson's disease were considered for a meta‐analysis. Pooled risk estimates and the risk of increased pulmonary artery pressure were calculated. Results:: The pooling of data from well‐designed observational studies documented that both pergolide (RR = 3.05 [1.71–5.44]) and cabergoline (RR = 6.38 [3.17–12.81]) represent a substantially increased risk of developing moderate to severe valvular regurgitation. In addition, pergolide, but not cabergoline, was associated with an increase in pulmonary artery pressure. Conclusions:: The present meta‐analysis confirmed a statistically significant association between pergolide and cabergoline treatment and the risk of moderate to severe valvular regurgitation. An association between bromocriptine and valvular regurgitation cannot be entirely ruled out. © 2011 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Danemark</li></country></list><tree><country name="Danemark"><noRegion><name sortKey="Rasmussen, Vibeke Guldbrand" sort="Rasmussen, Vibeke Guldbrand" uniqKey="Rasmussen V" first="Vibeke Guldbrand" last="Rasmussen">Vibeke Guldbrand Rasmussen</name></noRegion><name sortKey=" Stergaard, Karen" sort=" Stergaard, Karen" uniqKey=" Stergaard K" first="Karen" last=" Stergaard">Karen Stergaard</name><name sortKey="Dupont, Erik" sort="Dupont, Erik" uniqKey="Dupont E" first="Erik" last="Dupont">Erik Dupont</name><name sortKey="Poulsen, Steen Hvitfeldt" sort="Poulsen, Steen Hvitfeldt" uniqKey="Poulsen S" first="Steen Hvitfeldt" last="Poulsen">Steen Hvitfeldt Poulsen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000117 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000117 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:A3521F2ADEA85DDD6FC91814A070765A51D749C2
|texte= The risk of valvular regurgitation in patients with Parkinson's disease treated with dopamine receptor agonists
}}
| This area was generated with Dilib version V0.6.23. |  |